
Polynucleotides (Salmon DNA) Treatment
Polynucleotide (PN) treatments, derived from purified salmon DNA, are an advanced form of skin rejuvenation therapy known for their regenerative and healing properties. These long chains of DNA fragments help repair damaged skin, stimulate collagen and elastin production, and improve overall skin texture and hydration. By boosting fibroblast activity, they encourage natural skin renewal, making them effective for treating fine lines, wrinkles, acne scars, and dull or sagging skin. Polynucleotide therapy is commonly used on the face, under-eyes, neck, and even the scalp for hair restoration.
The treatment is typically administered through mesotherapy, involving a series of microinjections directly into the skin. It is minimally invasive with little to no downtime, and most people see visible results within a few weeks, with improvements continuing over time. The procedure is generally well-tolerated, with mild redness or swelling resolving quickly. Safe for most skin types, this therapy has become a popular option for those seeking natural, long-lasting skin revitalization with minimal risk of allergic reactions.
The Rise of Salmon DNA Treatments in Dubai Skincare
The rise of salmon DNA treatments in Dubai’s skincare scene reflects the growing demand for advanced, natural skin rejuvenation solutions. Polynucleotide therapy, often referred to as DNA salmon treatment, uses highly purified DNA fragments to stimulate skin regeneration, improve elasticity, and boost hydration from within. Popular in top aesthetic clinics across Dubai, this innovative treatment is especially favored for its ability to reduce fine lines, refine skin texture, and promote a radiant, youthful glow with minimal downtime. As more people seek non-invasive ways to maintain healthy, vibrant skin, salmon DNA skin booster have quickly become a go-to option for both locals and visitors alike.
The Science Behind the Treatment
Polynucleotide treatments work by introducing highly purified DNA fragments—most commonly sourced from salmon—into the skin through microinjections. These DNA strands act on a cellular level to stimulate fibroblast activity, encouraging the natural production of collagen and elastin, which are essential for firm, youthful skin. Additionally, polynucleotides help improve tissue repair, increase hydration, and neutralize harmful free radicals, creating an optimal environment for skin regeneration. The result is a smoother, more radiant complexion that improves gradually over a series of treatments with long-lasting effects.
Is This Treatment Right for You?
Polynucleotide (salmon DNA) treatments are ideal for anyone looking to improve skin texture, hydration, and overall radiance without undergoing invasive procedures. It’s especially beneficial for individuals dealing with fine lines, dullness, mild sagging, acne scars, or dehydrated skin. This treatment is suitable for all skin types and ages, whether you’re in your late 20s looking to maintain youthful skin or older and aiming to restore elasticity and firmness. It’s also a great option for those wanting a natural approach to skin rejuvenation, with minimal downtime and a low risk of adverse reactions.
Benefits of Salmon DNA Injection
Salmon DNA skin booster offer a wide range of benefits that go beyond surface-level skincare. By stimulating collagen and elastin production, they help improve skin firmness and elasticity, making fine lines and wrinkles less noticeable over time. The polynucleotides also enhance skin hydration and promote a smoother, more radiant complexion. This regenerative therapy supports cellular repair, making it effective for treating acne scars, under-eye dark circles, and overall skin dullness. With minimal downtime and a natural composition, it’s a safe, non-invasive way to achieve healthier, younger-looking skin.
Salmon DNA Injection Can Treat the Following Skin Concerns
1. Fine Lines & Wrinkles
- Reduces the appearance of crow’s feet, smile lines, and forehead wrinkles
- Boosts collagen and elastin for smoother, firmer skin
2. Dull & Dehydrated Skin
- Deeply hydrates and nourishes the skin
- Enhances natural glow and luminosity
3. Skin Sagging
- Improves skin elasticity and tightness
- Ideal for early signs of aging and loss of firmness
4. Uneven Skin Tone & Texture
- Promotes skin regeneration for a smoother texture
- Reduces pigmentation and brightens overall complexion
5. Acne Scars & Minor Scarring
- Supports tissue repair and skin renewal
- Fades post-acne marks and scars gradually
6. Large Pores
- Minimizes the appearance of enlarged pores
- Refines skin texture for a more polished look
7. Under-Eye Darkness & Puffiness
- Rejuvenates the delicate under-eye area
- Helps reduce dark circles and puffiness
8. Skin Redness & Sensitivity
- Calms inflammation and strengthens skin barrier
- Suitable for sensitive and rosacea-prone skin

What is PDRN (Polydeoxyribonucleotide) ?
PDRN (Polydeoxyribonucleotide) is a DNA-derived compound known for its regenerative and anti-inflammatory properties. Sourced primarily from DNA salmon due to its high compatibility with human skin, PDRN is composed of small DNA fragments that stimulate cellular repair and collagen production. It works by activating A2A adenosine receptors in the body, promoting tissue regeneration, improving blood flow, and accelerating the healing process. This makes it particularly effective in treating damaged or aging skin, reducing inflammation, and enhancing overall skin vitality.
In aesthetic medicine, PDRN is commonly used in skin booster treatments, microneedling serums, and injectables aimed at rejuvenating tired, dull, or aging skin. It helps improve elasticity, smooth out fine lines, and restore hydration, giving the skin a firmer, healthier, and more radiant appearance.
Why Salmon DNA is Perfect for Under-Eye Rejuvenation – Portofino Aesthetic Clinic
At Portofino Aesthetic Clinic, we trust the power of Salmon DNA for under-eye treatments because of its proven results. Our specialists confidently recommend it for targeting dark circles, puffiness, fine lines, and wrinkles. Salmon DNA skin booster is rich in polynucleotides that deeply hydrate and repair the delicate under-eye area, promoting cell regeneration and collagen production. It’s a natural, safe, and effective solution to refresh tired-looking eyes. With consistent treatments, you’ll notice brighter, firmer, and smoother under-eyes. Experience visible transformation with our expert care and advanced aesthetic solutions tailored just for you.

Post-Treatment Effects and Care
After a polynucleotide (salmon DNA) treatment, it’s normal to experience mild redness, swelling, or slight bruising at the injection sites—these effects are usually temporary and subside within 24 to 48 hours. Most people can return to their daily activities immediately, although it’s recommended to avoid intense exercise, direct sun exposure, and makeup for the first 24 hours. Keeping the skin clean and well-moisturized helps support the healing process. Since the treatment works on a cellular level, visible improvements typically begin within a week, with continued enhancement over the following weeks as collagen production increases. Regular maintenance sessions can help prolong and enhance the results.
Areas We Treat with Salmon DNA Therapy
Polynucleotide (salmon DNA) therapy is a versatile treatment suitable for multiple areas of the face and body. It is especially popular for delicate regions like the under-eyes, where it helps reduce dark circles, fine lines, and puffiness. The face, neck, and décolletage are also commonly treated to improve skin texture, hydration, and elasticity. In addition, it’s used on the hands to restore volume and smoothness, and even on the scalp to stimulate hair growth and improve scalp health. Thanks to its regenerative and hydrating properties, polynucleotide treatment is ideal for areas that show early signs of aging or need enhanced skin recovery.
Results and Aftercare
Following polynucleotide (salmon DNA) treatment, most patients begin to notice visible improvements in their skin within 7 to 10 days, with continued enhancement over the next few weeks as collagen and elastin production increase. The skin becomes more hydrated, smoother, and radiant, with reduced fine lines and improved elasticity. For optimal results, a course of 3 to 4 sessions spaced a few weeks apart is typically recommended, followed by maintenance treatments every few months.
Aftercare is simple but important—avoid touching the treated area for a few hours, and steer clear of heavy makeup, intense workouts, saunas, and sun exposure for 24 to 48 hours. Keeping the skin well-moisturized and using gentle skincare products helps support healing and maximize results. Always follow any personalized advice from your practitioner to ensure the best outcome.
FAQ’s Salmon DNA Injection Treatment
Salmon DNA treatment is an advanced skin rejuvenation therapy that uses polynucleotides (DNA fragments derived from salmon) to improve skin texture, elasticity, hydration, and overall appearance. It’s a popular non-surgical anti-aging solution.
The polynucleotides in salmon DNA stimulate collagen production, boost cell regeneration, and deeply hydrate the skin. This results in smoother, firmer, and more radiant skin over time.
Yes! Salmon DNA is biocompatible and highly purified, making it safe for most skin types. The treatment is minimally invasive and performed by trained aesthetic professionals.
Common treatment areas include the face, neck, décolleté, and hands — basically anywhere skin rejuvenation is desired.
Typically, a course of 3–4 sessions spaced 2–3 weeks apart is recommended for best results. Maintenance treatments may be done every 6–12 months.
This treatment is ideal for anyone looking to improve skin tone, texture, and elasticity, particularly those with dull, dehydrated, or aging skin.
Book your consultation at Portofino Aesthetic Clinic today to discover if Salmon DNA is right for you.

Affordable Salmon DNA Treatment Near You
Looking for a natural, effective way to rejuvenate your skin and restore its healthy glow? At Portofino Aesthetic Clinic Dubai, we offer Salmon DNA Injection designed to deeply hydrate, repair, and revitalize your skin from within. This advanced therapy boosts collagen production, enhances skin elasticity, and improves texture — making it ideal for dull, dehydrated, or aging skin. Our expert team uses the latest techniques to ensure safe, subtle, and beautiful results with minimal downtime. We provide Salmon DNA injections at affordable prices. If you’re searching for “Salmon DNA treatment near me,” visit our clinic for a personalized consultation and experience radiant, youthful skin — naturally.
Portofino Clinic | Restore Youthful Radiance with Salmon DNA Treatment
Looking to rejuvenate your appearance and restore your skin’s natural glow? Our advanced Salmon DNA Treatments are designed to deeply hydrate, repair damaged skin, and stimulate cell regeneration from within. Rich in nucleotides and amino acids, Salmon DNA helps boost collagen production, improve elasticity, and enhance overall skin texture for a smoother, more youthful appearance.
At Portofino Aesthetic Clinic Dubai, we specialize in customized Salmon DNA Injection to address dullness, fine lines, uneven tone, and signs of aging. Our expert team may also combine Salmon DNA therapy with other aesthetic solutions for a comprehensive skin rejuvenation approach tailored to your unique goals.
Say goodbye to tired, lackluster skin—and hello to a radiant, revitalized complexion! Contact Portofino Clinic today to schedule your personalized consultation and take the first step toward naturally beautiful, glowing skin.


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